What is the true impact of endometriosis on oocyte competence, defined as blastulation, euploidy and implantation?
To answer this question, a new study by the GeneraLife team in collaboration with the University of Catanzaro and Naples, has been published in the European Journal of Obstetrics & Gynecology and Reproductive Biology. Research has shown that the average rate of euploid blastocysts for each egg inseminated is identical in women with and without endometriosis, regardless of maternal age. And no difference was shown for all embryological standards studied.
Endometriosis could therefore not compromise the reproductive and developmental capacity of oocytes, although its impact on the number of oocytes retrieved cannot be ignored
Live birth rates per single euploid blastocyst transfer were also similar. No differences were reported in gestational and neonatal outcomes. Finally, the cumulative rates of live birth between completed cycles are identical.
“Endometriosis could therefore not compromise the reproductive and developmental capacity of oocytes, although its impact on the number of oocytes retrieved cannot be ignored“, comments the first author of the study, Alberto Vaiarelli, medical scientific coordinator of the GeneraLife center in Rome. “This information is critical for clinicians during counseling to outline an effective strategy for treating infertile patients with this disease”